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J Virol. 1982 July; 43(1): 1-7

Unique features of retrovirus expression in F/St mice.

H C Morse 3rd, C A Kozak, R A Yetter and J W Hartley

ABSTRACT

F/St mice are unique in producing high levels of both ecotropic and xenotropic murine leukemia virus. The high ecotropic virus phenotype is determined by three or more V (virus-inducing) loci. A single locus for inducibility of xenotropic murine leukemia virus was mapped to chromosome 1 close to, but possibly not allelic to, Bxv-1. Although the high ecotropic virus phenotype is phenotypically dominant, the high xenotropic virus phenotype was recessive in all crosses tested. Suppression of xenotropic murine leukemia virus is governed by a single gene which is not linked to the xenotropic V locus.

J Virol. 1982 July; 43(1): 1-7






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J. Bacteriol. Mol. Cell. Biol. Microbiol. Mol. Biol. Rev.
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Copyright © 1982 by the American Society for Microbiology. All rights reserved.