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J Virol. 1982 April; 42(1): 322-325

Shedding of vesicular stomatitis virus soluble glycoprotein by removal of carboxy-terminal peptide.

R A Irving and H P Ghosh

ABSTRACT

A comparison of partial NH2-terminal sequences of vesicular stomatitis viral glycoprotein G (molecular weight, 69,000) and the soluble extracellular glycoprotein antigen Gs (molecular weight, 57,000) shows that both of the sequences are identical. Tryptic fingerprint analyses show that Gs lacks the carboxy-terminal region containing the membrane-anchoring hydrophobic domain of G. These results suggest that Gs is formed by cleavage in the carboxy-terminal region of G.


J Virol. 1982 April; 42(1): 322-325




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