This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Strnad, B C Articles by Rabin, H Search for Related Content PubMed PubMed Citation Articles by Strnad, B C Articles by Rabin, H

 Previous Article  |  Next Article 

J Virol. 1982 January; 41(1): 258-264

Production and characterization of monoclonal antibodies against the Epstein-Barr virus membrane antigen.

ABSTRACT

Five murine hybridoma lines that produce monoclonal antibodies against Epstein-Barr virus membrane antigen (MA) were established. Immunoprecipitation experiments demonstrated that three of the antibodies precipitated both the 236,000 (236K) MA and the 212K MA. The other two antibodies precipitated the 86K MA. Antibodies against the 236K-212K MA and the 86K MA mediated complement-dependent cytolysis of Epstein-Barr-virus-infected cells. The antibodies against the 86K MA neutralized both the B95-8 and P3HR-1 viruses.

This article has been cited by other articles:

• Kirschner, A. N., Lowrey, A. S., Longnecker, R., Jardetzky, T. S. (2007). Binding-Site Interactions between Epstein-Barr Virus Fusion Proteins gp42 and gH/gL Reveal a Peptide That Inhibits both Epithelial and B-Cell Membrane Fusion. J. Virol. 81: 9216-9229 [Abstract] [Full Text]  
• Hutt-Fletcher, L. M. (2007). Epstein-Barr Virus Entry. J. Virol. 81: 7825-7832 [Full Text]  
• Kirschner, A. N., Omerovic, J., Popov, B., Longnecker, R., Jardetzky, T. S. (2006). Soluble Epstein-Barr Virus Glycoproteins gH, gL, and gp42 Form a 1:1:1 Stable Complex That Acts Like Soluble gp42 in B-Cell Fusion but Not in Epithelial Cell Fusion. J. Virol. 80: 9444-9454 [Abstract] [Full Text]  
• Omerovic, J., Lev, L., Longnecker, R. (2005). The Amino Terminus of Epstein-Barr Virus Glycoprotein gH Is Important for Fusion with Epithelial and B Cells. J. Virol. 79: 12408-12415 [Abstract] [Full Text]  
• McShane, M. P., Longnecker, R. (2004). Cell-surface expression of a mutated Epstein-Barr virus glycoprotein B allows fusion independent of other viral proteins. Proc. Natl. Acad. Sci. USA 101: 17474-17479 [Abstract] [Full Text]  
• Guerreiro-Cacais, A. O., Li, L., Donati, D., Bejarano, M. T., Morgan, A., Masucci, M. G., Hutt-Fletcher, L., Levitsky, V. (2004). Capacity of Epstein-Barr virus to infect monocytes and inhibit their development into dendritic cells is affected by the cell type supporting virus replication. J. Gen. Virol. 85: 2767-2778 [Abstract] [Full Text]  
• McShane, M. P., Mullen, M. M., Haan, K. M., Jardetzky, T. S., Longnecker, R. (2003). Mutational Analysis of the HLA Class II Interaction with Epstein-Barr Virus Glycoprotein 42. J. Virol. 77: 7655-7662 [Abstract] [Full Text]  
• Mori, Y., Yang, X., Akkapaiboon, P., Okuno, T., Yamanishi, K. (2003). Human Herpesvirus 6 Variant A Glycoprotein H-Glycoprotein L-Glycoprotein Q Complex Associates with Human CD46. J. Virol. 77: 4992-4999 [Abstract] [Full Text]  
• Wang, X., Kenyon, W. J., Li, Q., Mullberg, J., Hutt-Fletcher, L. M. (1998). Epstein-Barr Virus Uses Different Complexes of Glycoproteins gH and gL To Infect B Lymphocytes and Epithelial Cells. J. Virol. 72: 5552-5558 [Abstract] [Full Text]  
• Wang, X., Hutt-Fletcher, L. M. (1998). Epstein-Barr Virus Lacking Glycoprotein gp42 Can Bind to B Cells but Is Not Able To Infect. J. Virol. 72: 158-163 [Abstract] [Full Text]