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J Virol. 1981 September; 39(3): 861-869

Monoclonal antibodies specific for simian virus 40 tumor antigens.

E Harlow, L V Crawford, D C Pim and N M Williamson

ABSTRACT

Thirty hybridomas that secrete immunoglobulins against the simian virus 40 tumor antigens were isolated and cloned. Of these, 28 produced antibodies which bound to simian virus 40 large-T, and 2 produced antibodies which bound to the host 53,000-dalton protein. As in previous work, large-T antigen was found to have at least one determinant that it shared with small-t antigen and to have a minimum of six unique determinants. Several of the monoclonal antibodies from the L series hybridomas recognized determinants that were present on a subset of the large-T antigen from simian virus 40-transformed mouse cells. These monoclonal antibodies should be useful in studies of the structure and function of the simian virus 40 tumor antigens.

J Virol. 1981 September; 39(3): 861-869




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  • Porrás, A., Gaillard, S., Rundell, K. (1999). The Simian Virus 40 Small-t and Large-T Antigens Jointly Regulate Cell Cycle Reentry in Human Fibroblasts. J. Virol. 73: 3102-3107 [Abstract] [Full Text]  
  • Bond, J. A., Haughton, M. F., Rowson, J. M., Smith, P. J., Gire, V., Wynford-Thomas, D., Wyllie, F. S. (1999). Control of Replicative Life Span in Human Cells: Barriers to Clonal Expansion Intermediate Between M1 Senescence and M2 Crisis. Mol. Cell. Biol. 19: 3103-3114 [Abstract] [Full Text]  
  • Salewski, H., Bayer, T. A., Eidhoff, U., Preuss, U., Weggen, S., Scheidtmann, K. H. (1999). Increased Oncogenicity of Subclones of SV40 Large T-induced Neuroectodermal Tumor Cell Lines after Loss of Large T Expression and Concomitant Mutation in p53. Cancer Res. 59: 1980-1986 [Abstract] [Full Text]  
  • Akoum, A., Lavoie, J., Drouin, R., Jolicoeur, C., Lemay, A., Maheux, R., Khandjian, E. W. (1999). Physiological and Cytogenetic Characterization of Immortalized Human Endometriotic Cells Containing Episomal Simian Virus 40 DNA. Am. J. Pathol. 154: 1245-1257 [Abstract] [Full Text]  
  • Martelli, F., Livingston, D. M. (1999). Regulation of endogenous E2F1 stability by the retinoblastoma family proteins. Proc. Natl. Acad. Sci. USA 96: 2858-2863 [Abstract] [Full Text]  
  • Weisshart, K., Taneja, P., Jenne, A., Herbig, U., Simmons, D. T., Fanning, E. (1999). Two Regions of Simian Virus 40 T Antigen Determine Cooperativity of Double-Hexamer Assembly on the Viral Origin of DNA Replication and Promote Hexamer Interactions during Bidirectional Origin DNA Unwinding. J. Virol. 73: 2201-2211 [Abstract] [Full Text]  
  • Trowbridge, P. W., Roy, R., Simmons, D. T. (1999). Human Topoisomerase I Promotes Initiation of Simian Virus 40 DNA Replication In Vitro. Mol. Cell. Biol. 19: 1686-1694 [Abstract] [Full Text]  
  • Janus, F., Albrechtsen, N., Knippschild, U., Wiesmuller, L., Grosse, F., Deppert, W. (1999). Different Regulation of the p53 Core Domain Activities 3'-to-5' Exonuclease and Sequence-Specific DNA Binding. Mol. Cell. Biol. 19: 2155-2168 [Abstract] [Full Text]  
  • Herbig, U., Weisshart, K., Taneja, P., Fanning, E. (1999). Interaction of the Transcription Factor TFIID with Simian Virus 40 (SV40) Large T Antigen Interferes with Replication of SV40 DNA In Vitro. J. Virol. 73: 1099-1107 [Abstract] [Full Text]  
  • Cavender, J. F., Mummert, C., Tevethia, M. J. (1999). Transactivation of a Ribosomal Gene by Simian Virus 40 Large-T Antigen Requires at Least Three Activities of the Protein. J. Virol. 73: 214-224 [Abstract] [Full Text]  
  • Mateer, S. C., Fedorov, S. A., Mumby, M. C. (1998). Identification of Structural Elements Involved in the Interaction of Simian Virus 40 Small Tumor Antigen with Protein Phosphatase 2A. J. Biol. Chem. 273: 35339-35346 [Abstract] [Full Text]  
  • Higashino, F., Pipas, J. M., Shenk, T. (1998). Adenovirus E4orf6 oncoprotein modulates the function of the p53-related protein, p73. Proc. Natl. Acad. Sci. USA 95: 15683-15687 [Abstract] [Full Text]  
  • Jarvis, D. L., Wills, L., Burow, G., Bohlmeyer, D. A. (1998). Mutational Analysis of the N-Linked Glycans on Autographa californica Nucleopolyhedrovirus gp64. J. Virol. 72: 9459-9469 [Abstract] [Full Text]  
  • Howe, A. K., Gaillard, S., Bennett, J. S., Rundell, K. (1998). Cell Cycle Progression in Monkey Cells Expressing Simian Virus 40 Small t Antigen from Adenovirus Vectors. J. Virol. 72: 9637-9644 [Abstract] [Full Text]  
  • Weisshart, K., Taneja, P., Fanning, E. (1998). The Replication Protein A Binding Site in Simian Virus 40 (SV40) T Antigen and Its Role in the Initial Steps of SV40 DNA Replication. J. Virol. 72: 9771-9781 [Abstract] [Full Text]  
  • Marin, M. C., Jost, C. A., Irwin, M. S., DeCaprio, J. A., Caput, D., Kaelin, W. G. Jr. (1998). Viral Oncoproteins Discriminate between p53 and the p53 Homolog p73. Mol. Cell. Biol. 18: 6316-6324 [Abstract] [Full Text]  
  • Tang, H.-y., Zhao, K., Pizzolato, J. F., Fonarev, M., Langer, J. C., Manfredi, J. J. (1998). Constitutive Expression of the Cyclin-dependent Kinase Inhibitor p21 Is Transcriptionally Regulated by the Tumor Suppressor Protein p53. J. Biol. Chem. 273: 29156-29163 [Abstract] [Full Text]  
  • Iliopoulos, O., Ohh, M., Kaelin, W. G. Jr. (1998). pVHL19 is a biologically active product of the von Hippel-Lindau gene arising from internal translation initiation. Proc. Natl. Acad. Sci. USA 95: 11661-11666 [Abstract] [Full Text]  
  • Seghezzi, W., Chua, K., Shanahan, F., Gozani, O., Reed, R., Lees, E. (1998). Cyclin E Associates with Components of the Pre-mRNA Splicing Machinery in Mammalian Cells. Mol. Cell. Biol. 18: 4526-4536 [Abstract] [Full Text]  
  • Dallas, P. B., Cheney, I. W., Liao, D.-W., Bowrin, V., Byam, W., Pacchione, S., Kobayashi, R., Yaciuk, P., Moran, E. (1998). p300/CREB Binding Protein-Related Protein p270 Is a Component of Mammalian SWI/SNF Complexes. Mol. Cell. Biol. 18: 3596-3603 [Abstract] [Full Text]  
  • Robanus-Maandag, E., Dekker, M., van der Valk, M., Carrozza, M.-L., Jeanny, J.-C., Dannenberg, J.-H., Berns, A., te Riele, H. (1998). p107 is a suppressor of retinoblastoma development in pRb-deficient mice. Genes Dev. 12: 1599-1609 [Abstract] [Full Text]  
  • Lu, H., Taya, Y., Ikeda, M., Levine, A. J. (1998). Ultraviolet radiation, but not gamma  radiation or etoposide-induced DNA damage, results in the phosphorylation of the murine p53 protein at serine-389. Proc. Natl. Acad. Sci. USA 95: 6399-6402 [Abstract] [Full Text]  
  • Gire, V., Wynford-Thomas, D. (1998). Reinitiation of DNA Synthesis and Cell Division in Senescent Human Fibroblasts by Microinjection of Anti-p53 Antibodies. Mol. Cell. Biol. 18: 1611-1621 [Abstract] [Full Text]  
  • Harris, K. F., Christensen, J. B., Radany, E. H., Imperiale, M. J. (1998). Novel Mechanisms of E2F Induction by BK Virus Large-T Antigen: Requirement of Both the pRb-Binding and the J Domains. Mol. Cell. Biol. 18: 1746-1756 [Abstract] [Full Text]  
  • Lonergan, K. M., Iliopoulos, O., Ohh, M., Kamura, T., Conaway, R. C., Conaway, J. W., Kaelin, W. G. Jr. (1998). Regulation of Hypoxia-Inducible mRNAs by the von Hippel-Lindau Tumor Suppressor Protein Requires Binding to Complexes Containing Elongins B/C and Cul2. Mol. Cell. Biol. 18: 732-741 [Abstract] [Full Text]  
  • Vincent, S, Segretain, D, Nishikawa, S, Nishikawa, S., Sage, J, Cuzin, F, Rassoulzadegan, M (1998). Stage-specific expression of the Kit receptor and its ligand (KL) during male gametogenesis in the mouse: a Kit-KL interaction critical for meiosis. Development 125: 4585-4593 [Abstract]  
  • Ma, D., Gerard, R. D., Li, X.-Y., Alizadeh, H., Niederkorn, J. Y. (1997). Inhibition of Metastasis of Intraocular Melanomas by Adenovirus-Mediated Gene Transfer of Plasminogen Activator Inhibitor Type 1 (PAI-1) in an Athymic Mouse Model. Blood 90: 2738-2746 [Abstract] [Full Text]  
  • Yan, Y., Shay, J. W., Wright, W. E., Mumby, M. C. (1997). Inhibition of Protein Phosphatase Activity Induces p53-dependent Apoptosis in the Absence of p53 Transactivation. J. Biol. Chem. 272: 15220-15226 [Abstract] [Full Text]  
  • Campbell, K S, Mullane, K P, Aksoy, I A, Stubdal, H, Zalvide, J, Pipas, J M, Silver, P A, Roberts, T M, Schaffhausen, B S, DeCaprio, J A (1997). DnaJ/hsp40 chaperone domain of SV40 large T antigen promotes efficient viral DNA replication.. Genes Dev. 11: 1098-1110 [Abstract]  
  • Lens, D., J.J.C. De Schouwer, P., Hamoudi, R. A., Abdul-Rauf, M., Farahat, N., Matutes, E., Crook, T., Dyer, M. J.S., Catovsky, D. (1997). p53 Abnormalities in B-Cell Prolymphocytic Leukemia. Blood 89: 2015-2023 [Abstract] [Full Text]  
  • Mazars, G. R., Jat, P. S. (1997). Expression of p24, a novel p21Waf1/Cip1/Sdi1-related protein, correlates with measurement of the finite proliferative potential of rodent embryo fibroblasts. Proc. Natl. Acad. Sci. USA 94: 151-156 [Abstract] [Full Text]  
  • Kamalati, T., Jolin, H. E., Mitchell, P. J., Barker, K. T., Jackson, L. E., Dean, C. J., Page, M. J., Gusterson, B. A., Crompton, M. R. (1996). Brk, a Breast Tumor-derived Non-receptor Protein-tyrosine Kinase, Sensitizes Mammary Epithelial Cells to Epidermal Growth Factor. J. Biol. Chem. 271: 30956-30963 [Abstract] [Full Text]  
  • Friedlander, P., Legros, Y., Soussi, T., Prives, C. (1996). Regulation of Mutant p53 Temperature-sensitive DNA Binding. J. Biol. Chem. 271: 25468-25478 [Abstract] [Full Text]  
  • Eckner, R, Yao, T P, Oldread, E, Livingston, D M (1996). Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiation.. Genes Dev. 10: 2478-2490 [Abstract]  
  • Sepehrnia, B., Paz, I. B., Dasgupta, G., Momand, J. (1996). Heat Shock Protein 84Forms a Complex with Mutant p53 Protein Predominantly within a Cytoplasmic Compartment of the Cell. J. Biol. Chem. 271: 15084-15090 [Abstract] [Full Text]  
  • Du, W, Vidal, M, Xie, J E, Dyson, N (1996). RBF, a novel RB-related gene that regulates E2F activity and interacts with cyclin E in Drosophila.. Genes Dev. 10: 1206-1218 [Abstract]  
  • Bowman, T, Symonds, H, Gu, L, Yin, C, Oren, M, Van Dyke, T (1996). Tissue-specific inactivation of p53 tumor suppression in the mouse.. Genes Dev. 10: 826-835 [Abstract]  
  • Li, X., Coffino, P. (1996). Identification of a Region of p53 That Confers Lability. J. Biol. Chem. 271: 4447-4451 [Abstract] [Full Text]  
  • Hansen, S., Hupp, T. R., Lane, D. P. (1996). Allosteric Regulation of the Thermostability and DNA Binding Activity of Human p53 by Specific Interacting Proteins. J. Biol. Chem. 271: 3917-3924 [Abstract] [Full Text]  
  • Dickmanns, A, Bischoff, F., Marshallsay, C, Luhrmann, R, Ponstingl, H, Fanning, E (1996). The thermolability of nuclear protein import in tsBN2 cells is suppressed by microinjected Ran-GTP or Ran-GDP, but not by RanQ69L or RanT24N. J. Cell Sci. 109: 1449-1457 [Abstract]  
  • Akashi, M., Hachiya, M., Osawa, Y., Spirin, K., Suzuki, G., Koeffler, H. P. (1995). Irradiation Induces WAF1 Expression through a p53-independent Pathway in KG-1 Cells. J. Biol. Chem. 270: 19181-19187 [Abstract] [Full Text]  
  • Collins, B. S., Pipas, J. M. (1995). T Antigens Encoded by Replication-defective Simian Virus 40 Mutants dl1135 and 5080. J. Biol. Chem. 270: 15377-15384 [Abstract] [Full Text]  
  • Ewen, M E, Oliver, C J, Sluss, H K, Miller, S J, Peeper, D S (1995). p53-dependent repression of CDK4 translation in TGF-beta-induced G1 cell-cycle arrest.. Genes Dev. 9: 204-217 [Abstract]  
  • Kolatsi-Joannou, M, Woolf, A., Hardman, P, White, S., Gordge, M, Henderson, R. (1995). The hepatocyte growth factor/scatter factor (HGF/SF) receptor, met, transduces a morphogenetic signal in renal glomerular fibromuscular mesangial cells. J. Cell Sci. 108: 3703-3714 [Abstract]  
  • Midgley, C., Owens, B, Briscoe, C., Thomas, D., Lane, D., Hall, P. (1995). Coupling between gamma irradiation, p53 induction and the apoptotic response depends upon cell type in vivo. J. Cell Sci. 108: 1843-1848 [Abstract]  
  • Keough, R, Powell, B, Rogers, G (1995). Targeted expression of SV40 T antigen in the hair follicle of transgenic mice produces an aberrant hair phenotype. J. Cell Sci. 108: 957-966 [Abstract]  
  • Wagner, A J, Kokontis, J M, Hay, N (1994). Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1.. Genes Dev. 8: 2817-2830 [Abstract]  
  • Barak, Y, Gottlieb, E, Juven-Gershon, T, Oren, M (1994). Regulation of mdm2 expression by p53: alternative promoters produce transcripts with nonidentical translation potential.. Genes Dev. 8: 1739-1749 [Abstract]  
  • Lin, J, Chen, J, Elenbaas, B, Levine, A J (1994). Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein.. Genes Dev. 8: 1235-1246 [Abstract]  
  • Yew, P R, Liu, X, Berk, A J (1994). Adenovirus E1B oncoprotein tethers a transcriptional repression domain to p53.. Genes Dev. 8: 190-202 [Abstract]  
  • Zhu, L., Enders, G.H., Wu, C.-L., Starz, M.A., Moberg, K.H., Lees, J.A., Dyson, N., Harlow, E. (1994). Growth Suppression by Members of the Retinoblastoma Protein Family. Cold Spring Harb Symp Quant Biol 59: 75-84 [Abstract]  
  • Li, Y, Graham, C, Lacy, S, Duncan, A M, Whyte, P (1993). The adenovirus E1A-associated 130-kD protein is encoded by a member of the retinoblastoma gene family and physically interacts with cyclins A and E.. Genes Dev. 7: 2366-2377 [Abstract]  
  • Bargonetti, J, Manfredi, J J, Chen, X, Marshak, D R, Prives, C (1993). A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein.. Genes Dev. 7: 2565-2574 [Abstract]  
  • Helin, K, Wu, C L, Fattaey, A R, Lees, J A, Dynlacht, B D, Ngwu, C, Harlow, E (1993). Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation.. Genes Dev. 7: 1850-1861 [Abstract]  
  • Lowe, S W, Ruley, H E (1993). Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis.. Genes Dev. 7: 535-545 [Abstract]  
  • Vojtesek, B, Lane, D. (1993). Regulation of p53 protein expression in human breast cancer cell lines. J. Cell Sci. 105: 607-612 [Abstract]  


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