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J Virol. 1979 December; 32(3): 770-778

Protease required for processing picornaviral coat protein resides in the viral replicase gene.

A C Palmenberg, M A Pallansch and R R Rueckert

ABSTRACT

Partial purification of the encephalomyocarditis protease synthesized in extracts from rabbit reticulocytes shows that the activity responsible for cleaving coat precursor protein cosediments with a previously unmapped virus-coded protein with an apparent molecular weight of 20,000. Tryptic analysis shows that this protein is derived from protein D, a virus-coded component of the encephalomyocarditis RNA polymerase.


J Virol. 1979 December; 32(3): 770-778




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Copyright © 1979 by the American Society for Microbiology. All rights reserved.