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J Virol. 1979 December; 32(3): 1051-1056

Characterization of intracellular precursor polyproteins of Moloney murine leukemia virus.

V L Ng, T G Wood, D D Lyons and R B Arlinghaus

ABSTRACT

Intracellular Moloney murine leukemia viral precursor polyproteins were compared with mature viral proteins by immunoprecipitation and tryptic peptide mapping experiments. The results were consistent with precursor roles for Pr65gag, Pr200gag-pol, Pr135pol, and gPr83env. The glycosylated gag gene product gPr85gag, although containing sequences characteristic of all four core proteins plus additional sequences not found in Pr65gag, lacked a major tyrosine-containing p30 tryptic peptide, suggesting that gPr85gag is not processed to p30.

J Virol. 1979 December; 32(3): 1051-1056






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Copyright © 1979 by the American Society for Microbiology. All rights reserved.