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J Virol. 1979 October; 32(1): 234-239

Apparent posttranscriptional block to anaerobic induction of endogenous leukemia virus.

P A Whitaker-Dowling, K R Marotti and G R Anderson

ABSTRACT

Uninfected Fischer rat cells were induced by anaerobic stress to transcribe high levels of endogenous type C leukemia virus RNA. Complete 35S virus RNA with attached polyadenylic acid sequences was found associated with polysomes, indicating functional mRNA. Since no mature virus was released under these conditions, the presence of a posttranscriptional block to complete virus synthesis is strongly indicated.


J Virol. 1979 October; 32(1): 234-239







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Copyright © 1979 by the American Society for Microbiology. All rights reserved.