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J Virol. 1979 August; 31(2): 370-375

Host cell DNA chain initiation protein requirements for replication of bacteriophage G4 replicative-form DNA.

L B Dumas, S Goltz and D T Benesh

ABSTRACT

Bacteriophages G4ev1 and G4bs1 are simple temperature-resistant derivatives of wild-type G4 as demonstrated by restriction endonuclease analyses. The rate of replication of the duplex replicative-form DNA of these phages was normal in dnaB and dnaC mutants of the host, whereas the rate was markedly reduced in a dnaG host mutant at the restrictive temperature. We conclude that G4 duplex DNA replication requires the host cell dnaG protein, but not the dnaB and dnaC proteins. The reasons for the differences between our conclusions and those based on previously published data are documented and discussed.

J Virol. 1979 August; 31(2): 370-375






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Copyright © 1979 by the American Society for Microbiology. All rights reserved.