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J Virol. 1979 June; 30(3): 946-950

Nucleotide sequence of the self-priming 3' terminus of the single-stranded DNA extracted from the parvovirus Kilham rat virus.

L A Salzman and P Fabisch

ABSTRACT

The parvovirus genome is a linear, single-stranded DNA molecule with double-stranded hairpin termini. The 3' terminus can serve in vitro as a self-primer for the synthesis of a double-stranded viral DNA intermediate. We have sequenced the nucleotides in the 3' terminus and propose a model for the secondary structure of the terminus and the in vitro origin of replication for the complementary viral DNA strand.

J Virol. 1979 June; 30(3): 946-950






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Copyright © 1979 by the American Society for Microbiology. All rights reserved.