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J Virol. 1978 January; 25(1): 408-412

Inhibition of maturation of Rauscher leukemia virus by amino acid analogs.

G A Jamjoom, V L Ng and R B Arlinghaus

ABSTRACT

Synthesis of primary precursor polyproteins of Rauscher leukemia virus (RLV) core and envelope proteins occurs in the presence of amino acid analogs canavanine and p-fluorophenylalanine, but cleavage of these precursors is severely inhibited or slowed down. After treatment with these agents, the release of characteristic virus or stable virus-like particles is greatly depressed.

J Virol. 1978 January; 25(1): 408-412






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