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Structure and Development of Viruses as Observed in the Electron Microscope

VIII. Entry of Influenza Virus

Department of Microbiology, College of Physicians and Surgeons, Columbia University, New York, New York 10032

ABSTRACT

It is suggested that, after attachment of influenza virus to the cell, the viral coat disintegrates. With fusion of virus to the cytoplasmic membrane, the latter undergoes dissolution. Rupture of the viral core permits release of nucleoprotein directly into the cytoplasm. Stages in the process are illustrated.