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J Virol. 1976 April; 18(1): 356-360

Influenza virus RNA's in the cytoplasm of chicken embryo cells treated with 3'-deoxyadenosine.

C L Pridgen

ABSTRACT

3'-Deoxyadenosine (75 to 100 mug/ml) permitted analysis of the cytoplasmic influencza virus-specific RNAs synthesized early in the replicative cycle-a phase that has hitherto been obscurred by host cell RNA synthesis. In addition, late in the cycle (6 to 8) complementary virus-specific RNA's were the predominantly labeled species, suggesting that higher concentrations of 3'-deoxyadenosine selectively inhibit influenza viral genome replication.

J Virol. 1976 April; 18(1): 356-360






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J. Bacteriol. Mol. Cell. Biol. Microbiol. Mol. Biol. Rev.
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Copyright © 1976 by the American Society for Microbiology. All rights reserved.