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J Virol. 1975 May; 15(5): 1276-1280
Copyright © 1975 American Society for Microbiology. All Rights Reserved.

Heteroduplex Mapping of Heat-Resistant Deletion Mutants of Bacteriophage T5

^* Department of Biology, University of Virginia, Charlottesville, Virginia 22901
¹ Department of Biology, Johns Hopkins University, Baltimore, Maryland 21218

ABSTRACT

The bacteriophage T5 is known to spontaneously generate deletion mutants (st mutants) exhibiting enhanced resistance to heat inactivation in citrate buffer. A series of such mutants has been isolated and the deletions visualized by electron microscopy of heteroduplex molecules. The deletions are found to cluster in one region of the chromosome.

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