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J Virol. 1974 December; 14(6): 1470-1475
Copyright © 1974 American Society for Microbiology. All Rights Reserved.

Induction of Prophage SPO2 in Bacillus subtilis by 6-(para)-Hydroxyphenylazouracil

Fré Arwert and Lars Rutberg

Department of Bacteriology, Karolinska Institutet, Stockholm, Sweden

ABSTRACT

DNA replication in Bacillus subtilis is reversibly inhibited by 6-(para)-hydroxyphenylazouracil (HpUra) (1971), whereas replication of temperature phage SPO2 is not affected by the drug. Experiments are presented which show that HpUra will induce bacteria lysogenic for SPO2. Also, prophage {varphi}105, which is sensitive to the drug, is induced by HpUra. Induction of SPO2 lysogenics in the presence of HpUra gives selective synthesis of SPO2 DNA.

J Virol. 1974 December; 14(6): 1470-1475
Copyright © 1974 American Society for Microbiology. All Rights Reserved.





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Copyright © 1974 by the American Society for Microbiology. All rights reserved.