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J Virol. 1974 October; 14(4): 878-885
Copyright © 1974 American Society for Microbiology. All Rights Reserved.

Structure of Isometric Viruses Containing Nonidentical Polypeptide Chains

A. Keith Dunker

1 Memorial Sloan-Kettering Cancer Center, New York, New York 10021

ABSTRACT

The theory of Caspar and Klug (1962) for the structure of isometric viruses has been generalized to the case in which the identical repeating unit is composed of n nonidentical polypeptide chains. This modified theory accounts for the structure of picornaviruses, the lambda phage head, cowpea mosaic virus, and {varphi}X174, while at the same time conserving the principle of having identical subunits in identical environments. Furthermore, the modified theory suggests amending the triangulation number to T[n] for capsids with n nonidentical polypeptide chains as the repeating unit.

J Virol. 1974 October; 14(4): 878-885
Copyright © 1974 American Society for Microbiology. All Rights Reserved.





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Copyright © 1974 by the American Society for Microbiology. All rights reserved.