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Comparison of 6/94 Virus and Sendai Virus RNA by RNA-RNA Hybridization

Départment de Biologie Moléculaire, Université de Genève, Geneva, Switzerland
The Wistar Institute, Philadelphia, Pennsylvania 19104

ABSTRACT

The genomic RNA of 6/94 virus, an agent isolated from the brains of multiple sclerosis patients, was studied for sequence homology by RNA-RNA hybridization with closely related Sendai virus and another paramyxovirus virus, Newcastle disease virus. It was found that the genomic RNA of 6/94 virus hybridizes equally as well to the virus-specific 18S RNA found in Sendai-infected cells as that of Sendai virus.

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