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J Virol. 1973 June; 11(6): 815-822
Copyright © 1973 American Society for Microbiology. All Rights Reserved.

Virus-Induced Proteins in Pseudorabies-Infected Cells I. Acid-Extractable Proteins of the Nucleus

¹ Department of Biochemistry, University of Glasgow, Glasgow, G12 8QQ, Scotland

ABSTRACT

Three basic proteins have been identified in chromatin preparations from pseudorabies virus-infected cells. They appear to be virus specified and are similar in size and charge to host histones; one difference however is that they contain tryptophan. All are produced by 3 h postinfection, and two (IP II and III) seem to be arginine rich. Three similar proteins are also found in herpes simplex MP 17-infected cells, and two of these co-electrophorese with two of the pseudorabies proteins. Partially purified preparations of pseudorabies virus contain low amounts of all three proteins.