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J Virol. 1973 February; 11(2): 338-340
Copyright © 1973 American Society for Microbiology. All Rights Reserved.

Resistance of Bacteriophage PBS2 Infection to 6-(p-Hydroxyphenylazo)-Uracil, an Inhibitor of Bacillus subtilis Deoxyribonucleic Acid Synthesis

Alan R. Price and Suzanne M. Fogt

1 Department of Biological Chemistry, The University of Michigan, Ann Arbor, Michigan 48104

ABSTRACT

6-(p-Hydroxyphenylazo)-uracil (HPUra), an inhibitor of semiconservative deoxyribonucleic acid (DNA) synthesis in Bacillus subtilis, does not prevent (but slightly reduces the rate of) replication of the uracil-containing DNA phage PBS2. Our observations are consistent with the hypothesis that all B. subtilis phages which are resistant to HPUra are able to induce a new DNA polymerase activity.

J Virol. 1973 February; 11(2): 338-340
Copyright © 1973 American Society for Microbiology. All Rights Reserved.





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Copyright © 1973 by the American Society for Microbiology. All rights reserved.