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J Virol. 1973 January; 11(1): 61-68
Copyright © 1973 American Society for Microbiology. All Rights Reserved.
Department of Virology and Epidemiology, Baylor College of Medicine, Houston, Texas 77025
ABSTRACT
The nucleic acid of Pichinde virus was found to be single-stranded ribonucleic acid (RNA) as determined by sensitivity to ribonuclease, by alkaline degradation, by buoyant density in cesium sulfate, and by analysis of the base composition. The RNA of the virion could be separated into five components which had sedimentation coefficients corresponding to 31S, 28S, 22S, 18S and 4 to 6S. The 28S, 18S, and possibly the 4 to 6S RNAs appear to be derived from host cell components incorporated into the virion, whereas the 31S and 22S components appear to represent the genome of the virus.
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