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J Virol. 1967 December; 1(6): 1255-1264
Copyright © 1967 American Society for Microbiology. All Rights Reserved.

Vaccinia Virus Infection of Synchronized Pig Kidney Cells

Rose Mary Groyon and Alexis J. Kniazeff

Naval Biological Laboratory, School of Public Health, University of California, Berkeley, California 94625

ABSTRACT

Vaccinia virus replication was studied in pig kidney (PK-15) cells synchronized by excess thymidine treatment. It was found that virus replication with concomitant inhibition of mitosis can occur at any period in the life cycle of the cell except for the narrow span of time from late prophase through telophase. Cells infected at this time continue to divide, and vaccinia does not replicate until cell division is complete.

J Virol. 1967 December; 1(6): 1255-1264
Copyright © 1967 American Society for Microbiology. All Rights Reserved.





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J. Bacteriol. Mol. Cell. Biol. Microbiol. Mol. Biol. Rev.
Clin. Vaccine Immunol. ALL ASM JOURNALS

Copyright © 1967 by the American Society for Microbiology. All rights reserved.